KEGG   Homo sapiens (human): 91039
Entry
91039             CDS       T01001                                 
Symbol
DPP9, DP9, DPLP9, DPP_IX, DPRP-2, DPRP2, HATIS, IMD111
Name
(RefSeq) dipeptidyl peptidase 9
  KO
K08656  dipeptidyl-peptidase 9 [EC:3.4.14.5]
Organism
hsa  Homo sapiens (human)
Disease
H01725  Primary immunodeficiency disease
Drug target
Talabostat (DG02903): D05989 D05990
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    91039 (DPP9)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.14  Dipeptidyl-peptidases and tripeptidyl-peptidases
    3.4.14.5  dipeptidyl-peptidase IV
     91039 (DPP9)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S9: prolyl oligopeptidase family
   91039 (DPP9)
SSDB
Motif
Pfam: DPPIV_N Peptidase_S9 Dpp_8_9_N Peptidase_S15 BD-FAE Esterase Abhydrolase_6 Abhydrolase_1 Hydrolase_4 DLH
Other DBs
NCBI-GeneID: 91039
NCBI-ProteinID: NP_631898
OMIM: 608258
HGNC: 18648
Ensembl: ENSG00000142002
UniProt: Q86TI2
Structure
Position
19:complement(4675227..4723842)
AA seq 892 aa
MRKVKKLRLDKENTGSWRSFSLNSEGAERMATTGTPTADRGDAAATDDPAARFQVQKHSW
DGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEI
PKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLF
LFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWV
ANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLK
TLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIV
STQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTE
NEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGF
CHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETK
LVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPC
VHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHAL
QPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEG
ALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAI
AGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENV
HFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL
NT seq 2679 nt   +upstreamnt  +downstreamnt
atgcggaaggttaagaaactgcgcctggacaaggagaacaccggaagttggagaagcttc
tcgctgaattccgagggggctgagaggatggccaccaccgggaccccaacggccgaccga
ggcgacgcagccgccacagatgacccggccgcccgcttccaggtgcagaagcactcgtgg
gacgggctccggagcatcatccacggcagccgcaagtactcgggcctcattgtcaacaag
gcgccccacgacttccagtttgtgcagaagacggatgagtctgggccccactcccaccgc
ctctactacctgggaatgccatatggcagccgagagaactccctcctctactctgagatt
cccaagaaggtccggaaagaggctctgctgctcctgtcctggaagcagatgctggatcat
ttccaggccacgccccaccatggggtctactctcgggaggaggagctgctgagggagcgg
aaacgcctgggggtcttcggcatcacctcctacgacttccacagcgagagtggcctcttc
ctcttccaggccagcaacagcctcttccactgccgcgacggcggcaagaacggcttcatg
gtgtcccctatgaaaccgctggaaatcaagacccagtgctcagggccccggatggacccc
aaaatctgccctgccgaccctgccttcttctccttcatcaataacagcgacctgtgggtg
gccaacatcgagacaggcgaggagcggcggctgaccttctgccaccaaggtttatccaat
gtcctggatgaccccaagtctgcgggtgtggccaccttcgtcatacaggaagagttcgac
cgcttcactgggtactggtggtgccccacagcctcctgggaaggttcagagggcctcaag
acgctgcgaatcctgtatgaggaagtcgatgagtccgaggtggaggtcattcacgtcccc
tctcctgcgctagaagaaaggaagacggactcgtatcggtaccccaggacaggcagcaag
aatcccaagattgccttgaaactggctgagttccagactgacagccagggcaagatcgtc
tcgacccaggagaaggagctggtgcagcccttcagctcgctgttcccgaaggtggagtac
atcgccagggccgggtggacccgggatggcaaatacgcctgggccatgttcctggaccgg
ccccagcagtggctccagctcgtcctcctccccccggccctgttcatcccgagcacagag
aatgaggagcagcggctagcctctgccagagctgtccccaggaatgtccagccgtatgtg
gtgtacgaggaggtcaccaacgtctggatcaatgttcatgacatcttctatcccttcccc
caatcagagggagaggacgagctctgctttctccgcgccaatgaatgcaagaccggcttc
tgccatttgtacaaagtcaccgccgttttaaaatcccagggctacgattggagtgagccc
ttcagccccggggaagatgaatttaagtgccccattaaggaagagattgctctgaccagc
ggtgaatgggaggttttggcgaggcacggctccaagatctgggtcaatgaggagaccaag
ctggtgtacttccagggcaccaaggacacgccgctggagcaccacctctacgtggtcagc
tatgaggcggccggcgagatcgtacgcctcaccacgcccggcttctcccatagctgctcc
atgagccagaacttcgacatgttcgtcagccactacagcagcgtgagcacgccgccctgc
gtgcacgtctacaagctgagcggccccgacgacgaccccctgcacaagcagccccgcttc
tgggctagcatgatggaggcagccagctgccccccggattatgttcctccagagatcttc
catttccacacgcgctcggatgtgcggctctacggcatgatctacaagccccacgccttg
cagccagggaagaagcaccccaccgtcctctttgtatatggaggcccccaggtgcagctg
gtgaataactccttcaaaggcatcaagtacttgcggctcaacacactggcctccctgggc
tacgccgtggttgtgattgacggcaggggctcctgtcagcgagggcttcggttcgaaggg
gccctgaaaaaccaaatgggccaggtggagatcgaggaccaggtggagggcctgcagttc
gtggccgagaagtatggcttcatcgacctgagccgagttgccatccatggctggtcctac
gggggcttcctctcgctcatggggctaatccacaagccccaggtgttcaaggtggccatc
gcgggtgccccggtcaccgtctggatggcctacgacacagggtacactgagcgctacatg
gacgtccctgagaacaaccagcacggctatgaggcgggttccgtggccctgcacgtggag
aagctgcccaatgagcccaaccgcttgcttatcctccacggcttcctggacgaaaacgtg
cactttttccacacaaacttcctcgtctcccaactgatccgagcagggaaaccttaccag
ctccagatctaccccaacgagagacacagtattcgctgccccgagtcgggcgagcactat
gaagtcacgttgctgcactttctacaggaatacctctga

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Ontology (3)   
   KEGG BRITE (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Drug (2)   
   KEGG DRUG (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (39)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (37)   
DNA sequence (86)   
   RefSeq(nuc) (48)   
   GenBank (19)   
   EMBL (19)   
3D Structure (11)   
   PDB (11)   
Protein domain (10)   
   Pfam (10)   
All databases (171)   

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